10-4091
Etrumadenant
Größe
£211.00
- SKU:
- 10-4091
- Zusätzliche Namen:
- AB928
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 426.48
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 2239273-34-6
- Immunogen:
- GPCR
- Weitere Details:
- Etrumadenant is a potent dual adenosine receptor antagonist (Ki: A2AR = 1.5 nM; A2BR = 2.0 nM)1.2 It blocked immunosuppressive signaling and increased cytokine secretion and proliferation in CAR T cells.3 Etrumadenant acted syntergistically with epirubicin and a nanomedicine formulation to reverse adenosine-mediated immunosuppression in a triple negative breast cancer model.4
- Versandbedingungen:
- Ambient