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10-4090

TIC10

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£153.00

SKU:
10-4090
Zusätzliche Namen:
Dordaviprone|ONC201
Physischer Zustand:
Solid
Molekulargewicht:
386.49
Reinheit:
98%
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
1616632-77-9
Immunogen:
Protease
Weitere Details:
TIC10 is novel anti-cancer compound that acts via early-stage integrated stress response activation leading to selective cancer cell death.1-3 TIC10 potently activates mitochondrial caseinolytic protease P (ClpP) causing eIF2A Alpha-independent induction of ATF4 and Akt/ERK/Foxo3a/DR5/TRAIL-dependent apoptosis.4 Clinical ly useful anticancer agent.
Versandbedingungen:
Ambient