10-4060
P053
Größe
£158.00
- SKU:
- 10-4060
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 342.41
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1022417-69-1
- Immunogen:
- Phosphatase
- Weitere Details:
- P053 is a selective inhibitor of protein phosphatase 5 (PP5) - IC50 = 706 nM.1 PP5 regulates signaling cascades that are responsible for tumor initiation, progression, and metastasis and is thus an interesting anticancer target. P053 induced apoptosis in 786-O renal carcinoma cells. Inhibition of PP5 by P053 prevents deactivation of the death effector protein FADD and activates the extrinsic apoptosis pathway complex II.
- Versandbedingungen:
- Ambient