10-4046
SGC-iMLLT
Größe
£173.00
- SKU:
- 10-4046
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 388.48
- Reinheit:
- >98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 2255338-25-9
- Immunogen:
- Bromodomain
- Weitere Details:
- Potent (IC50 = 260 nM) inhibitor of the YEATS domain of MLLT1/3.1 YEATS domain containing proteins bind acetyl and crotonyl marks on histone tails. Selective against the two other human YEATS domains YEATS2/4 and 48 bromodomains. YEATS containing MLL-ENL leukemic cells display increased sensitivity to SGC-iMLLT versus control AML cells.2
- Versandbedingungen:
- Ambient