10-4037
BZ1
Größe
£163.00
- SKU:
- 10-4037
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 278.74
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 2766623-38-3
- Immunogen:
- Bromodomain|Transcription factor
- Weitere Details:
- Potent (Kd = 6.3 nM; IC50 = 67 nM BPTF Alphascreen) inhibitor of the bromodomain PHD finger transcription factor (BPTF). It displays >350-fold selectivity over BET bromodomains. BZ1 sensitized 4T1 mouse breast cancer cells to doxorubicin treatment. BPTF inhibition represents a potential strategy for the inhibition of nucleosome remodeling factor (NURF) and exploration of its function.
- Versandbedingungen:
- Ambient