10-4018
A-196
Größe
£168.00
- SKU:
- 10-4018
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 359.25
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1982372-88-2
- Immunogen:
- Protein methyltransferase
- Weitere Details:
- A-196 (1982372-88-2) is a potent and selective (over 29 other methyltransferases) inhibitor of the protein lysine methyltransferases SUV420H1(IC50 = 25 nM) and SUV420H2 (IC50 = 144 nM). It substantially inhibited non-homologous end-joining (NHEJ)-directed DNA repair but not homology-directed repair(HDR) in cells treated with ionizing radiation. A-196 is active in cells and displayed no toxicity in several cell lines.
- Versandbedingungen:
- Ambient