10-4017
Lomeguatrib
Größe
£153.00
- SKU:
- 10-4017
- Zusätzliche Namen:
- O6-(4-Bromothenyl)guanine
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 326.17
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 192441-08-0
- Immunogen:
- DNA|Methyltransferase|Nucleic acid methylation
- Weitere Details:
- Lomeguatrib is a potent (IC50 = 9 nM) inhibitor of O6-Methylguanine-DNA Methyltransferase (MGMT), an important DNA repair protein.1 It is currently being investigated in cancers that have acquired resistant to the chemotherapeutic temozolomide2-5, as well as other chemotherapeutics6,7.
- Versandbedingungen:
- Ambient