10-4011
Selinexor
Größe
£163.00
- SKU:
- 10-4011
- Zusätzliche Namen:
- KPT-330
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 443.31
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1393477-72-9
- Weitere Details:
- Selinexor is a potent inhibitor of the nuclear export receptor, chromosome region maintenance 1 (CRM1; Exportin-1 (XPO1)). It exhibited potent growth suppression in various T-cell acute lymphoblastic leukemia (T-ALL) cells (IC50's = 34-203 nM)1 and pancreatic cancer cells (IC50 ~ 150 nM)2. Selinexor is being investigated as a possible chemotherapeutic in treating multiple types of cancer.3-8 Currently in clinical trials.
- Versandbedingungen:
- Ambient