10-3992
Sibiriline
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- SKU:
- 10-3992
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 210.24
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1346526-26-8
- Immunogen:
- Antioxidant
- Weitere Details:
- Sibiriline is a novel dual inhibitor of necroptosis and ferroptosis.1,2 It prevents necroptosis via inhibition of RIPK1 (IC50 = 1.1 uM) and ferroptosis via inhibition of phospholipid peroxidation acting as a radical trapping antioxidant. Sibiriline displayed neuroprotective effects in a mouse model of Parkinson's disease.
- Versandbedingungen:
- Ambient