10-3977
C19-9
Größe
£149.00
- SKU:
- 10-3977
- Zusätzliche Namen:
- (E)-N'-(3-Hydroxy-4-methoxybenzylidene)-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 314.35
- Reinheit:
- >98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1477482-47-5
- Weitere Details:
- C19-9 (1477482-47-5) is a novel non-RGD inhibitor of the integrin A AlphavB Beta3 receptor (KD = 102 nM). It was active against the human prostate carcinoma epithelial cell line 22RV1 (IC50 = 467 nM) and human prostate cancer organoids (IC50 = 652 nM). C19-9 was active in vivo in 22RV1 mouse xenografts and blocked growth in enzalutamide-resistant mouse CRPC xenografts.
- Versandbedingungen:
- Ambient