10-3901
Elafibranor
Größe
£163.00
- SKU:
- 10-3901
- Zusätzliche Namen:
- GFT505
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 384.49
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 923978-27-2
- Immunogen:
- Transcription factor
- Weitere Details:
- Elafibranor is a dual PPARalpha/delta agonist (EC50 PPARalpha = 10-20 nM; PPARdelta = 100-150 nM).1 It was able to decrease plasma triglycerides levels1, increase HDL cholesterol levels in human studies1, and improve hepatic and peripheral insulin sensitivity2. Elafibranor's antidiabetic effects in db/db were without the adverse cardiac effects seen in PPARgamma agonism.3 Elafibranor has also been shown to have therapeutic promise in the treatment of nonalcoholic steatohepatitis (NASH).4-6
- Versandbedingungen:
- Ambient