10-3893
Baricitinib
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£147.00
- SKU:
- 10-3893
- Zusätzliche Namen:
- INCB028050|LY3009104
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 371.42
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1187594-09-7
- Immunogen:
- Kinase
- Weitere Details:
- Baricitinib, approved by the FDA for two inflammatory disorders, rheumatoid arthritis and alopecia areata, selectively inhibits Janus kinase 1 (IC50 = 5.9 nM) and 2 (5.7 nM), over 3 (0.56 uM).1 It thereby blocks JAK/STAT signaling, reducing cytokine release and suppressing the innate and adaptive immune systems.1,2 Was recently shown to significantly improve COVID-19 symptoms in a preliminary human trial, presumably through suppression of the cytokine release syndrome ("cytokine storm") induced by SARS-CoV-2 infection.3
- Versandbedingungen:
- Ambient