10-3880
JNJ-63533054
Größe
£168.00
- SKU:
- 10-3880
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 316.78
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1802326-66-4
- Immunogen:
- GPCR
- Weitere Details:
- Potent and selective brain-penetrant GPR139 agonist (EC50=16 nM) an orphan G-protein-coupled receptor expressed in the CNS.1 Tritium-labeled JNJ-63533054 binds to cell membranes expressing GPR139 and can be displaced by putative endogenous ligands.2 Decreases compulsive-like alcohol drinking and hyperalgesia in alcohol-dependent rodents.3 Suppresses morphine intake in a mouse self-administration model.4
- Versandbedingungen:
- Ambient