TG-100572 HCl

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£173.00

SKU:: 10-3778
Physischer Zustand:: Solid
Molekulargewicht:: 512.44
Reinheit:: >98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 867331-64-4
Immunogen:: Kinase
Weitere Details:: TG-100572 is a multi-targeted kinase inhibitor that inhibits selected receptor kinases and Src kinases. IC50s = 2, 7, 2, 16, 13 VEGFR1, VEGFR2, FGFR1, FGFR2 PDGFRB Beta and 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for Fgr, Fyn, Hck, Lck, Lyn, Src and Yes respectively.1 It suppresses choroidal neovascularization and retinal edema1. Blocks angiogenesis caused by HSV infection in the mouse eye.2 A prodrug strategy has been employed for topically applied AMD treatment.3