10-3739
Ozanimod
Größe
£153.00
- SKU:
- 10-3739
- Zusätzliche Namen:
- RPC1063
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 404.47
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1306760-87-1
- Weitere Details:
- Ozanimod binds to human recombinant sphingosine-1-phosphate receptor S1P1 and S1P5 receptors in a competitive radioligand binding assay. Agonism at S1P1 receptors induced receptor internalization whereas S1P5 did not.1 It displays anti-inflammatory activity and is in clinical use for multiple sclerosis2 and inflammatory bowel disease3. It reduces chronic inflammation and alleviates kidney pathology in systemic lupus erythematosus in a mouse model.4
- Versandbedingungen:
- Ambient