10-3657
JQ1-PA
Größe
Auf Anfrage
- SKU:
- 10-3657
- Zusätzliche Namen:
- (+)-JQ1 PA
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 437.95
- Reinheit:
- >95%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 2115701-93-2
- Immunogen:
- Bromodomain
- Weitere Details:
- JQ1-PA (2115701-93-2) is an alkyne-linked analog of the BET-bromodomain inhibitor JQ1. It can be used to create PROTACs targeting BET-bromodomains by click-conjugating with various E3 ligase ligands. It can also be click-conjugated to fluorescent dyes for imaging applications. JQ1-PA can be used to harness BET-bromodomain nuclear import activity. When conjugated to an antisense oligonucleotide (ASO), it enhances nuclear accumulation which drives increased potency and efficacy of ASOs.2
- Versandbedingungen:
- Ambient