10-3652
SCR7 pyrazine
Größe
£168.00
- SKU:
- 10-3652
- Zusätzliche Namen:
- SCR7-G|SCR7-X
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 332.38
- Reinheit:
- >98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 14892-97-8
- Immunogen:
- DNA
- Weitere Details:
- SCR7 pyrazine enhances the efficiency of precise genome editing with CRISPR/Cas9 up to 19-fold via inhibition of nonhomologous end joining (NHEJ).1,2 May be employed in an optimized CRISPR/Cas9 method to target methylation in a site-specific manner enabling maintenance of gene silencing in vitro and in vivo.3 SCR7 pyrazine exhibits greater activity against DNA ligases I and III than DNA ligase IV.4 Induces cancer cell death via inhibition of NHEJ and potentiates the effect of double strand break-inducing therapeutic modalities.4,5
- Versandbedingungen:
- Ambient