10-3573
4-Octyl itaconate
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£149.00
- SKU:
- 10-3573
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 242.32
- Reinheit:
- >98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 3133-16-2
- Immunogen:
- Transcription factor
- Weitere Details:
- 4-Octyl itaconate is a cell-permeable analog of itaconic acid which activates the anti-inflammatory transcription factor Nrf2 via alkylation of KEAP1.1 It inhibits various forms of cell death including ferroptosis2 and gasdermin B-mediated pyroptosis3 while inducing secretion of anti-inflammatory proteins4 and promoting a wound-resolving phenotype in pro-inflammatory macrophages5.
- Versandbedingungen:
- Ambient