10-3564
Verrucarin A
Größe
£226.00
- SKU:
- 10-3564
- Zusätzliche Namen:
- 379-Y|Glutinosin-I|Muconomycin-A|Myrothecin-I|NSC-126728
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 502.56
- Reinheit:
- >98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 3148-09-2
- Immunogen:
- Transcription factor
- Weitere Details:
- A macrocyclic trichothecene mycotoxin from Myrothecium sp. It is a potent and selective inhibitor of the steroid receptor coactivator-3 and selectively down-regulates its expression.1 It is cytotoxic to multiple types of cancer cells at low nM concentrations (IC50=4.9 nM for HepG2 cells) but not toward normal liver cells.1,2 It enhances TNFA Alpha-induced3 and TRAIL-induced apoptosis4. It reduces phosphorylation of IREA Alpha and inhibits tunicamycin-induced ER stress in FaO rat liver cells.5
- Versandbedingungen:
- Ambient