Verteporfin

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£173.00

SKU:: 10-3487
Zusätzliche Namen:: BPD-MA|CL 318,952
Physischer Zustand:: Solid
Molekulargewicht:: 718.79
Reinheit:: 98%
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 129497-78-5
Immunogen:: Transcription factor
Weitere Details:: Verteporfin inhibits transcription by YAP/TAZ, IC50 = 2.5 uM, (via disruption of YAP-TEAD interaction) inhibiting autophagy and halting proliferation of cancer and cancer stem cell lines.1,2 Inhibits autophagosome formation.3 Reverses differentiation of Src-overexpressing embryonic stem cells.4 May be used to ablate unwanted neovasculature in the eye, esophageal mucosa, and elsewhere using light to create damaging free radicals.5