10-3467
Piericidin A
Größe
£144.00
- SKU:
- 10-3467
- Zusätzliche Namen:
- AR-054|Piericidin A1|Shaoguanmycin B|SN 198E
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 415.57
- Reinheit:
- 94%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 2738-64-9
- Immunogen:
- Antibiotic|Energy production
- Weitere Details:
- A potent inhibitor of the mitochondrial and bacterial type I NADH-ubiquinone oxidoreductase (complex I).1 Piericidin A is a ubiquinone analog which binds to the ubiquinone binding site of the enzyme.2 It is an extremely useful tool for exploring the role of complex I in mitochondrial function in both normal and pathophysiology.3-5 Prevents upregulation of GRP78 and induces cell death in glucose-deprived, etoposide-resistant HT-29 cells (IC50=7.7 nM).6
- Versandbedingungen:
- Ambient