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10-3451

TPPU

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£177.00

SKU:
10-3451
Physischer Zustand:
Solid
Molekulargewicht:
359.35
Reinheit:
>98%
Aufreinigung:
HPLC Purified
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
1222780-33-7
Weitere Details:
TPPU is a potent and selective inhibitor of both murine and human soluble epoxide hydrolase, IC50=2.8 and 3.7 nM respectively.1 It alleviated blood brain barrier damage and attenuated neuronal injury in a mouse intracerebral hemorrhage model2 and displays neuroprotective effects in ischemic injury3. It reduces neuroinflammation in a mouse model of Alzheimer's disease.4 It improves insulin resistance and reduced hypertension in mouse models.5 Cell permeable and active in vivo.
Versandbedingungen:
Ambient