Erastin

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£163.00

SKU:: 10-3406
Physischer Zustand:: Solid
Molekulargewicht:: 547.04
Reinheit:: 98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 571203-78-6
Immunogen:: Glutathione|Ion channel
Weitere Details:: Ferroptosis inducer.1 Inhibits the cystine-glutamate antiporter, system Xc- leading to activation of an ER stress response.2 Inhibition of system Xc- leads to cysteine starvation, glutathione depletion and induction of ferroptosis.3 Also blocks mitochondrial voltage-dependent anion channels (specifically VDAC2 and 3).4