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10-3396

PCI-34051

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£158.00

SKU:
10-3396
Physischer Zustand:
Solid
Molekulargewicht:
296.33
Reinheit:
>98%
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
950762-95-5
Immunogen:
Protein deacetylase
Weitere Details:
PCI-34051 is a potent and selective HDAC8 inhibitor (IC50=10 nM) with greater than 200-fold selectivity over HDACs 1, 2, 3, 6, 10.1 Unlike broad-spectrum HDAC inhibitors, it does not cause detectable histone or tubulin acetylation.1 Studies employing PCI-34051 showed that HDAC8 catalyzes the hydrolysis of long chain fatty acyl lysine.2 It is a very useful tool for exploring the role of HDAC8 in cellular function.3-6
Versandbedingungen:
Ambient