10-3375
AC1903
Größe
£168.00
- SKU:
- 10-3375
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 303.36
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 831234-13-0
- Immunogen:
- Ion channel
- Weitere Details:
- A potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis. It also provided therapeutic benefit in a rat model of hypertensive proteineuric kidney disease. The use of this selective tool compound provided a mechanistic rationale for targeting TRPC5 channels in progressive chronic kidney diseases and paves the way for the discovery of new therapeutics. Active in vivo.
- Versandbedingungen:
- Ambient