10-3079
Z-Phe-Tyr-CHO
Größe
£129.00
- SKU:
- 10-3079
- Zusätzliche Namen:
- SB-412515|Z-FY-CHO|Z-Phe-Tyr-Aldehyde
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 446.50
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 167498-29-5
- Immunogen:
- Protease
- Weitere Details:
- A potent and selective inhibitor of cathepsin L, IC50=0.85 nM 1 selective over cathepsin B and calpain II (IC50s=85.1 and 184 nM respectively). Suppresses osteoclastic pit formation at 1.5 nM and markedly inhibited parathyroid hormone-stimulated osteoclastic bone resorption.2 Also inhibits cathepsin K (Kis=0.052 and 1.57 nM for cat L and cat K respectively) and partially provides the basis for the finding that cathepsin K is the protease responsible for osteoclastic bone resorption.3 Provides partial protection against serum and potassium deprivation-induced neuronal death.4 Active in vivo.2
- Versandbedingungen:
- Ambient