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10-3075

Tolcapone

Größe

£149.00

SKU:
10-3075
Zusätzliche Namen:
Ro 40-7592
Physischer Zustand:
Solid
Molekulargewicht:
273.24
Reinheit:
98%
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
134308-13-7
Immunogen:
Dopamine|Methyltransferase
Weitere Details:
Catechol O-methyltransferase inhibitor (COMT), inhibiting both brain and peripheral enzymes.1 Potent inhibitor of alpha-synuclein and beta-amyloid oligomerization and fibrillogenesis protecting against extracellular toxicity.2 Binds to transthyretin (TTR) with high affinity (21 to 58 nM) and inhibits TTR aggregation in human plasma and prevents TTR-induced cytotoxicity in vitro. Stabilizes TTR in mice and humans in vivo.3 Inhibits O-methylation of exogenous polyphenols such as EGCG.4 Cell permeable. Orally bioavailable
Versandbedingungen:
Ambient