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10-3035

Nilvadipine

Größe

£168.00

SKU:
10-3035
Zusätzliche Namen:
FR34235
Physischer Zustand:
Solid
Molekulargewicht:
385.38
Reinheit:
98%
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
75530-68-6
Immunogen:
Ion channel|Kinase
Weitere Details:
A novel DHP L-type Ca2+ channel blocker that also inhibits Syk.1 Blocks AB Beta production, APPB Beta secretion and reduces BACE-1 expression in CHO cells over-expressing AB Beta in vitro. Enhances clearance of AB Beta across the blood brain barrier in vivo. Reduces brain AB Beta levels in a mouse tauopathy model.1 Clinically useful antihypertensive agent.2 Has been shown to prevent cognitive decline in some clinical trials.3 Produces a protective effect on glutamate neurotoxicity in retinal ganglion cells, an effect not shared by other L-type Ca2+ channel blockers such as nifedipine and diltiazem.4
Versandbedingungen:
Ambient