Kenpaullone

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£177.00

SKU:: 10-3028
Zusätzliche Namen:: NSC 664704
Physischer Zustand:: Solid
Molekulargewicht:: 327.18
Reinheit:: >98%
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 142273-20-9
Immunogen:: Kinase
Weitere Details:: Inhibits GSK-3B Beta (IC50=0.23 uM) as well as several cyclin-dependent kinases (CDKs), IC50=0.4, 0.68 and 0.85 uM for cdk1, cdk2 and cdk5 respectively.1-3 Induces pluripotent stem cells from somatic cells4 and increases direct neural conversion of human fibroblasts5 when used with other small molecules. Inhibits Kruppel-Like Factor 4 (KLF4) reducing autoimmune arthritis in the collagen-induced arthritis mouse model.6