10-3016
ARV-110
Größe
£153.00
- SKU:
- 10-3016
- Zusätzliche Namen:
- Bavdegalutamide
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 812.3
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 2222112-77-6
- Immunogen:
- PROTAC®|Transcription factor
- Weitere Details:
- ARV-110 is a CRBN-based PROTAC protein degrader that recruits the cereblon-containing E3 ubiquitin ligase to direct the proteasomal degradation of the androgen receptor (AR). It selectively degrades wild-type AR and most clinically relevant mutants with low nM potency.1 ARV-110 is the first PROTAC to enter the clinic.2 Analytical methods suitable for pharmacokinetic studies have been developed.3
- Versandbedingungen:
- Ambient