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10-2838

Obeticholic acid

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£149.00

SKU:
10-2838
Zusätzliche Namen:
6-ECDCA|6-Ethylchenodeoxycholic acid
Physischer Zustand:
Solid
Molekulargewicht:
420.63
Reinheit:
98%
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
459789-99-2
Immunogen:
Transcription factor
Weitere Details:
A novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM). Displays anticholeretic activity in a rat model of cholestasis.1 Promotes adipocyte differentiation and regulates adipose cell function.2 Normalizes insulin sensitivity in a rabbit model of metabolic syndrome.3 A potentially new therapeutic agent for management of non-alcoholic fatty liver disease4 and NASH5. Displays therapeutic benefit in patients with primary biliary cirrhosis.6 Active in vivo.
Versandbedingungen:
Ambient