10-2736
8-pCPT-2-O-Me-cAMP-AM
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£193.00
- SKU:
- 10-2736
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 557.91
- Reinheit:
- 97%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 1152197-23-3
- Immunogen:
- GTPase
- Weitere Details:
- A potent, cell-permeable Epac (exchange protein directly activated by cAMP) activator1. Induces RAP1 activation and insulin secretion in pancreatic beta cell lines2-5. Induces vascular relaxation in rat mesenteric artery6. The acetoxymethyl ester confers increased cell-permeability and is cleaved by endogenous esterases to yield the active compound, 8-pCPT-2'-O-Me-cAMP. Addition to cell cultures should be done in serum-free media as esterases in serum will cleave the acetoxymethyl ester and reduce cell permeability.
- Versandbedingungen:
- Ambient