10-2631
Triptolide
Größe
£134.00
- SKU:
- 10-2631
- Zusätzliche Namen:
- PG490
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 360.40
- Reinheit:
- 98%
- Aufreinigung:
- HPLC Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 38748-32-2
- Immunogen:
- Transcription factor
- Weitere Details:
- Possesses potent immunosuppressive and anti-inflammatory activity. Irreversibly inhibits eukaryotic transcription via covalent binding to XPB, a subunit of the transcription factor TFIIH.1 Blocks transactivation of NFK KappaB.2 Exhibits potent antiproliferative activity in 60 cancer cell lines (average IC50 = 12 nM) and synergizes with other anticancer agents.3 Inhibits the inflammatory response and remarkably decreases production of TNF-A Alpha, IL-1B Beta and IL-6 in a rat model of rheumatoid arthritis.4
- Versandbedingungen:
- Ambient