Monastrol

Größe

£173.00

SKU:: 10-2629
Physischer Zustand:: Solid
Molekulargewicht:: 292.35
Reinheit:: 98%
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 254753-54-3
Immunogen:: Cytoskeleton
Weitere Details:: Potent, cell-permeable, small molecule inhibitor of mitosis. Monastrol-arrested cells are characterized by monopolar spindles.1 Does not affect other motor proteins or tubulin. Specifically inhibits the mitotic molecular motor kinesin Eg5, a motor protein required for spindle formation (IC50 = 14 uM).2 Mimics the effect of amyloid B Beta on long term potentiation in a cellular model of learning and memory.3 Enhances regeneration of adult axons.4