10-2524
Stattic
Größe
£144.00
- SKU:
- 10-2524
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 211.20
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 19983-44-9
- Immunogen:
- Transcription factor
- Weitere Details:
- STAT3 inhibitor. Inhibits binding of tyrosine-phosphorylated peptides to STAT3 SH2 domain and inhibiting STAT3 activation, dimerization and nuclear translocation1. Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. Induces apoptosis in STAT3-dependent cancer cell lines. Alkyates four cysteine residues on STAT32. Exhibits potent antitumor activity3. Protects against angiotensin II-induced vascular dysfunction and hypertension4. An extremely useful tool to probe involvement of STAT3 in cellular signaling.
- Versandbedingungen:
- Ambient