TTNPB

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£164.00

SKU:: 10-2517
Zusätzliche Namen:: AGN-191183|Arotinoid acid|Ro 13-7410
Physischer Zustand:: Solid
Molekulargewicht:: 348.49
Reinheit:: >98%
Aufreinigung:: HPLC Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Focus Biomolecules
CAS Number:: 71441-28-6
Immunogen:: Retinoid receptor and related|Transcription factor
Weitere Details:: Highly potent and selective retinoic acid analog acting as an RAR agonist (EC50 = 21, 4 and 2.4 nM for RARA Alpha, RARB Beta and RARG Gamma respectively).1 TTNPB has been extensively used in stem cell differentiation protocols. It enhances reprogramming efficiency in chemically induced pluripotent stem cells.2 Chondrocytes are robustly induced from human pluripotent stem cells by treatment with CHIR99021 and TTNPB.3 TTNPB alone, efficiently converts primary adult mouse fibroblasts into dermal papilla cell-like cells.4 Can be used in combination with other small molecules for induction of mouse totipotent stem cells.5