10-2493
SB-3CT
Größe
£177.00
- SKU:
- 10-2493
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 306.39
- Reinheit:
- >98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 292605-14-2
- Immunogen:
- Protease
- Weitere Details:
- SB-3CT (292605-14-2) is a potent and selective inhibitor of MMP2 (Ki=28 nm) which also inhibits MMP9 (Ki=400 nM).1 The drug rescues laminin from proteolysis and neurons from apoptosis in a transient focal cerebral ischemia mouse model.2 It abrogates elevation of blood brain barrier (BBB) permeability in mouse Parkinson's disease models3 and improves specific neurobehavioral deficits in a mouse model of Alzheimer's disease4. BBB permeable.
- Versandbedingungen:
- Ambient