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10-2491

CUDC-101

Größe

£168.00

SKU:
10-2491
Physischer Zustand:
Solid
Molekulargewicht:
434.49
Reinheit:
99%
Aufreinigung:
HPLC Purified
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
1012054-59-9
Immunogen:
Kinase|Protein deacetylase
Weitere Details:
A novel hybrid dual-acting HDAC and receptor tyrosine kinase inhibitor. It is a potent HDAC inhibitor which also inhibits EGFR and HER2, IC50 = 4.4, 2.4 and 15.7 nM respectively.1 It not only blocks EGFR and HER2 but also attenuates multiple compensatory pathways such as AKT, HER3 and MET which enable tumor cells to escape the effects of conventional EGFR/HER2 inhibitors.1,2
Versandbedingungen:
Ambient