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10-2387

Nocodazole

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£149.00

SKU:
10-2387
Zusätzliche Namen:
R-17934
Physischer Zustand:
Solid
Molekulargewicht:
301.32
Reinheit:
98%
Lagerbedingungen:
RT
Hersteller:
Focus Biomolecules
CAS Number:
31430-18-9
Immunogen:
Cytoskeleton|Lysosome
Weitere Details:
Nocodazole is an antimitotic agent that disrupts microtubules by binding to B Beta tubulin and thereby inhibiting microtubule dynamics, disruption of mitotic spindle function, and fragmentation of the Golgi complex.1,2 Arrests cell cycle at G2/M phase. Stimulates the intrinsic GTPase activity of tubulin.3 Nocodazole activates the JNK/SAPK signaling pathway and induces apoptosis in a variety of cell lines.4 Increases Cas9-mediated editing frequencies5 and increased CRISPR-mediated HDR DNA repair6. Cell permeable.
Versandbedingungen:
Ambient