10-2311
Honokiol
Größe
£153.00
- SKU:
- 10-2311
- Zusätzliche Namen:
- NSC-293100
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 266.34
- Reinheit:
- >98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 35354-74-6
- Immunogen:
- Protein deacetylase|Transcription factor
- Weitere Details:
- Honokiol is a natural product that acts as a SIRT3 activator. It increases mitochondrial oxygen consumption and reduces ROS production in wild type but not SIRT3-KO cells.1 It reversed cardiac hypertrophy in mice1 and rescued myocardial and mitochondrial energetics in type 2 diabetic rats2. It was shown to increase SIRT3 expression in the hippocampus and attenuated surgery-induced memory loss, neuronal apoptosis, neuroinflammation and oxidative damage.3 It increases expression of adipocyte gene markers, gene-involved lipolysis and glucose transport and in general, promotes insulin sensitivity.4
- Versandbedingungen:
- Ambient