10-2280
L-Cycloserine
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£149.00
- SKU:
- 10-2280
- Zusätzliche Namen:
- L-(-)-Cycloserine|S-Cycloserine
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 102.09
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 339-72-0
- Weitere Details:
- L-Cycloserine down-regulates sphingolipid biosynthesis via inhibition of serine palmitoyltransferase (3-ketodihydrosphingosine synthetase).1 The L isomer was shown to be 100-fold more potent than the D isomer at inhibition of the brain microsomal enzyme.1 It is a useful pharmacological agent for lowering sphingolipid levels in cells2 as well as in animal models3. Inhibition of de novo ceramide biosynthesis with L-cycloserine positively affected the senescent phenotype, restoring neuronal signaling and reducing mitochondrial dysfunction in a cortical neuronal model of senescence.4
- Versandbedingungen:
- Ambient