10-2183
Vatalanib 2HCl
Größe
£149.00
- SKU:
- 10-2183
- Zusätzliche Namen:
- CGP-79787|PTK-787|ZK222584
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 419.73
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 212141-51-0
- Immunogen:
- Kinase
- Weitere Details:
- Potent, selective inhibitor of the VEGFR tyrosine kinases VEGFR-1 (Flt-1, IC50 = 77 nM) and VEGFR-2 (FLK-1/KDR, IC50 = 37 nM)1. Weaker inhibitor of other tyrosine kinases including PDGFR-B Beta (IC50 = 580 nM), c-KIT (IC50 = 730 nM), FLT-4 (IC50 = 660 nM) and c-FMS (IC50 = 1.4 uM). Inactive against the EGFR, c-SRC, v-ABL, and protein kinase CA Alpha (IC50 > 10 uM). Inhibits the growth of multiple myeloma cells in the bone marrow microenvironment2.
- Versandbedingungen:
- Ambient