10-2135
Erlotinib HCl
Größe
£134.00
- SKU:
- 10-2135
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 429.91
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 183319-69-9
- Immunogen:
- Kinase
- Weitere Details:
- Potent inhibitor of EGFR tyrosine kinase (IC50 = 2 nM)1. Potent inhibitor of mutant JAK2-V617F2. Weaker inhibitor of ErbB-2 kinase (Ki = 1 uM) ErbB-4 kinase (Ki = 1.5 uM)3. HDAC inhibitors sensitize for erlotinib activity in EGFR-mutated and wildtype non-small cell lung cancer (NSCLC) cells4. A clinically effective agent for NSCLC5.
- Versandbedingungen:
- Ambient