10-2131
MS-275
Größe
£149.00
- SKU:
- 10-2131
- Zusätzliche Namen:
- Entinostat|SNDX-275
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 376.42
- Reinheit:
- 98%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 209783-80-2
- Immunogen:
- Protein deacetylase
- Weitere Details:
- Potent HDAC inhibitor. Selective for HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 uM) and HDAC8 (IC50 > 100 uM).1 In vivo, MS-275 has been shown to inhibit tumor growth via induction of the tumor supressors p21WAF1/CIP1 and gelsolin2 and to block cell proliferation in a variety of cancer cell lines3,4. The compound has also shown significant anti-rheumatic activity in rat and mouse arthritis models.5
- Versandbedingungen:
- Ambient