10-2129
Dovitinib
Größe
£173.00
- SKU:
- 10-2129
- Zusätzliche Namen:
- CHIR258|TKI-258
- Physischer Zustand:
- Solid
- Molekulargewicht:
- 392.43
- Reinheit:
- 99%
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Focus Biomolecules
- CAS Number:
- 405169-16-6
- Immunogen:
- Kinase
- Weitere Details:
- Potent kinase inhibitor. Inhibits FLT3 (IC50 = 1 nM), c-KIT (IC50 = 2 nM), FGFR (IC50 = 8 nM), VEGFR1/2/3 (IC50 = 10 nM), PDGFRB Beta (IC50 = 27 nM), and CSF-1R (IC50 = 36 nM).1 Active in cell culture and in whole animals. Selectively blocks the growth B9 cells transformed by wild type, or activated mutant FGFR3. Induces apoptosis, or sensitizes cells to induction of apoptosis by other means in a variety of cancer cell lines.
- Versandbedingungen:
- Ambient