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10-2121

Bexarotene

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SKU:
10-2121
Zusätzliche Namen:
LGD-1069|SR-11247
Physischer Zustand:
Solid
Molekulargewicht:
348.49
Reinheit:
98%
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
153559-49-0
Immunogen:
Retinoid receptor and related|Transcription factor
Weitere Details:
A highly potent and selective retinoid X receptor (RXR) agonist (EC50=28, 25, 20 nM for RXRA Alpha, B Beta, G Gamma respectively)1. Clinically useful antineoplastic agent for cutaneous T-cell lymphoma2 Causes complete regression of mammary carcinoma3. Bexarotene significantly increases clearance of soluble B Beta-amyloid in a mouse Alzheimer's model and increases cognitive ability4. Reverses apoE4-driven brain pathology and behavioral deficits in vivo5.
Versandbedingungen:
Ambient