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10-2114

Withaferin A

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£163.00

SKU:
10-2114
Zusätzliche Namen:
NSC-101088
Physischer Zustand:
Solid
Molekulargewicht:
470.60
Reinheit:
99%
Aufreinigung:
HPLC Purified
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
5119-48-2
Immunogen:
Cytoskeleton
Weitere Details:
Displays potent antiangiogenesis activity inhibiting endothelial cell sprouting in vitro (IC50 = 12 nM) and in vivo.1 Potently inhibits NF-K KappaB activation by preventing TNFA Alpha-induced activation of IKKB Beta.2 Covalently binds to the intermediate filament protein, vimentin3 inducing its disassembly and serine 56 phosphorylation4. Inhibits reactive gliosis and blocks TNFA Alpha-mediated neuronal apoptosis in in vivo models.5
Versandbedingungen:
Ambient