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10-2111

Tunicamycin

Größe

£182.00

SKU:
10-2111
Physischer Zustand:
Solid
Molekulargewicht:
Avg 840.0
Reinheit:
99%
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
11089-65-9
Immunogen:
Antibiotic|ER/Golgi|UPR (Unfolded Protein Response)
Weitere Details:
Fermentation product from Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs varying in the number of carbon atoms in the fatty acid chain. The structure shown above is for tunicamycin B (the C15 homolog) Potent inhibitor of GlcNAc phosphotransferase which thereby inhibits glycoprotein biosynthesis1. Causes endoplasmic reticulum stress-induced autophagy2 and unfolded protein response3. Arrests cell cycle in late G14.
Versandbedingungen:
Ambient