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10-1600

CaCCinh-A01

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£149.00

SKU:
10-1600
Physischer Zustand:
Solid
Molekulargewicht:
347.43
Reinheit:
>98%
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
407587-33-1
Immunogen:
Ion channel
Weitere Details:
CaCCInh-A01 is a potent inhibitor of TMEM16A (IC50 = 2.1 mM), a calcium-activated chloride channel1. Blockade of TMEM16A with CaCCInh-A01 protects against renal fibrosis2, reduces blood brain barrier permeability, attenuates brain infarct size and neurological deficits after ischemic stroke3, and induces apoptosis and cell cycle arrest in various epithelium-originated cancer cells4.
Versandbedingungen:
Ambient