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10-1567

Compound 115-7c

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£187.00

SKU:
10-1567
Zusätzliche Namen:
SW02
Physischer Zustand:
Solid
Molekulargewicht:
477.34
Reinheit:
98%
Lagerbedingungen:
-20[o]C
Hersteller:
Focus Biomolecules
CAS Number:
908074-72-6
Immunogen:
Chaperone|HSP (Heat shock protein)
Weitere Details:
Acts as an artificial co-chaperone for HSP701. The activity of compound 115-7c mirrors those of HSP40 stimulating the ATPase and protein-folding activities of prokaryotic HSP70. Increases tau levels in cell lines overexpressing tau2. Induces solubilization of polyglutamine and exacerbates polyQ-mediated toxicity3,4. An important probe for understanding HSP70 functions4
Versandbedingungen:
Ambient